Clinical Pharmacology & Pharmacometrics
Unlock the power of data to enhance your clinical outcomes
With our in-depth expertise in Clinical Pharmacology & Pharmacometrics, we offer a comprehensive suite of services tailored to your unique needs, including pharmacokinetic (PK) / pharmacodynamic (PD) analysis, population PK analysis and exposure-response analysis. Through meticulous data analysis and advanced modeling-informed drug development (MIDD) methods, D2V Clinical empowers our clients to gain valuable insights into drug behavior, optimize dosing strategies, and ultimately enhance clinical outcomes.
- PK/PD analysis to study the behavioral and physiological effects of drug concentration
- Population PK analysis to identify variability and covariates for drug exposure and response
- Exposure-response analysis for therapeutic windows & benefit/risk profiling
- Dose optimization and individualization to optimize dosing regimens with maximized therapeutic benefit while minimizing the risk of adverse effects
- Modeling-informed drug development (MIDD) to provide decision support and guide protocol development, study conduct, and data analysis to optimize clinical trial outcomes and resource allocation
Trust the team that has completed 80+ FDA PK/PD oncology reviews
Our Processes
Population PK analysis process
Data collection
Individual PK profiles
Population PK model building
Model fitting
Parameter estimates
Variability analysis
Covariate analysis
